文物概况:理解书面文物物质性的泛米学方法
Marina Creydt1,2, Markus Fischer1,2
1Institute of Food Chemistry, Hamburg School of Food Science, University of Hamburg, Grindelallee 117, 20146 Hamburg, Germany.
Molecules (Basel, Switzerland)
|June 28, 2023
概括
这篇评论探讨了分析书面文物的奥米克战略 (基因组学,蛋白质组学,代谢组学,金属组学,同位素组学). 这些方法揭示了物质信息,元信息,并有助于保存和真实性评估.
科学领域:
- 对历史文献进行科学分析.
- 对文物研究的多学科方法.
背景情况:
- 书面文物包含了文本之外的宝贵信息.
- 传统的分析方法通常在范围和细节上是有限的.
研究的目的:
- 审查对分析书面文物的奥米克策略.
- 突出结合多个omics学科 (泛omics) 的潜力.
主要方法:
- 基因组学,蛋白质组学,代谢组学,金属组学和同位素组学方法.
- 高分辨率,非有针对性的分析策略.
- 讨论手稿的各种采样技术.
主要成果:
- 奥米克斯分析提供了对文物材料和元信息 (例如微生物残留物) 的洞察.
- 这些技术可以确定真实性,评估毒性,并为保护策略提供信息.
- 巴诺米克斯提供了增强的数据解释和附加值.
结论:
- 欧米克技术为了解书面文物的生产和历史提供了强大的工具.
- 这些方法的应用有助于保护和管理文化遗产.
- 未来的研究应该专注于整合各种omics数据进行全面的文物分析.
相关概念视频
Methods of Documentation II: POMR
1.0K
The Problem-Oriented Medical Record (POMR) revolutionized medical record-keeping by introducing a systematic approach focusing on the patient's problems rather than merely listing symptoms. Dr. Lawrence Weed's introduction of this method in the 1960s marked a significant advancement in medical documentation. The POMR framework consists of four key components: the database, problem list, plan of care, and progress notes.
1.0K
Structuralism
709
Structuralism, an early psychological theory developed by Wilhelm Wundt and his student Edward Bradford Titchener, sought to dissect the human mind into its most fundamental components. Wundt's groundbreaking work in his laboratory set the stage for Titchener to define structuralism's goal as cataloging the "atoms" of the mind—sensations, images, and feelings—akin to how chemists identify elements of matter.
Titchener's approach to structuralism was unique. He...
Titchener's approach to structuralism was unique. He...
709
Methods of Documentation III: PIE
1.4K
Problem-intervention-evaluation (PIE) is a systematic approach to documentation used in healthcare settings for clinical decision-making and patient care planning. It is a structured approach to organizing patient data based on problems, interventions, and evaluations. Here's a breakdown of its key features and considerations:
1.4K
Methods of Documentation I: Source-Oriented Records
1.2K
Source-oriented records, or SOR, are medical record-keeping organized by the data source. The SOR system was first developed in the mid-1900s to organize the growing patient data in hospitals and other healthcare facilities.
In an SOR, each discipline involved in patient care maintains a separate medical record section. This record-keeping method enables easy tracking of patient progress and ensures healthcare staff have access to up-to-date information.
Key Attributes include the following:
In an SOR, each discipline involved in patient care maintains a separate medical record section. This record-keeping method enables easy tracking of patient progress and ensures healthcare staff have access to up-to-date information.
Key Attributes include the following:
1.2K
Archival Research
16.0K
Some researchers gain access to large amounts of data without interacting with a single research participant. Instead, they use existing records to answer various research questions. This type of research approach is known as archival research. Archival research relies on looking at past records or data sets to look for interesting patterns or relationships. For example, a researcher might access the academic records of all individuals who enrolled in college within the past ten years and...
16.0K
Scanning Electron Microscopy
4.3K
A scanning electron microscope (SEM) is used to study the surface features of a sample by using an electron beam that scans the sample surface in a two-dimensional manner. Typically, areas between ~1 centimeter to 5 micrometers in width can be imaged. SEM can be used to image bacteria, viruses, tissues as well as larger samples like insects. Conventional SEM gives a magnification ranging from 20X to 30,000X and spatial resolution of 50 to 100 nanometers.
Fundamental Principles
Accelerated...
Fundamental Principles
Accelerated...
4.3K


