梅科家族的类类植物及其生物活动
Sandra Amalia Riyadi1, Al Arofatus Naini1, Unang Supratman1,2
1Department of Chemistry, Faculty of Mathematic and Natural Sciences, Universitas Padjadjaran, Jatinangor, Sumedang 45363, Indonesia.
Molecules (Basel, Switzerland)
|June 28, 2023
概括
这篇综述详细介绍了来自梅属植物的413种类类植物,强调了它们的生物合成和多样化的生物活动. 这些天然产品显示出传统医学和新药发现的潜力.
科学领域:
- 自然产品化学 自然产品化学
- 植物化学 植物化学
- 药用化学 医学化学
背景情况:
- 塞斯基特类是植物衍生化合物,有三个异烯单元,起源于法纳西尔酸盐 (FPP).
- 梅花科家族是各种生物活动的丰富多样的类类植物的丰富来源.
- 梅里亚系类植物的研究跨越了55年,涉及多种植物部位.
研究的目的:
- 综合审查来自Meliaceae家族 (1968-2023) 的孤立和挥发性类类.
- 为这些天然产品的未来研究和开发提供参考.
- 为了探索Meliaceae sesquiterpenoids的生物合成途径和生物活动.
主要方法:
- 使用SciFinder,谷歌学者和PubMed进行了广泛的文献搜索.
- 对报告从各种Meliaceae植物部位中分离塞斯基特类的研究进行分析.
- 编制和分类已识别的基类化合物及其活动.
主要成果:
- 确定了大约413种属于各种结构类型 (例如,eudesmane,cadinane, guaiane) 的四聚烯化合物.
- 尤德斯曼型的甲类化合物占已识别的化合物总量的27%.
- 评估活动包括抗微生物,抗糖尿病,抗氧化,抗质,抗病毒和细胞毒性质.
结论:
- 梅花系植物是结构多样化的类植物的重要来源.
- 已识别的类类植物具有广泛的生物活性,支持它们在传统医学中的应用.
- 这些发现强调了梅里亚系类类植物在新药发现方面的潜力.
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