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全血与中国成年人认知表现之间的关系

Zijian Lu¹, Ruikun He², Ying Zhang²

¹Academy of Nutrition and Health, Hubei Province Key Laboratory of Occupational Hazard Identification and Control, School of Public Health, Wuhan University of Science and Technology, Wuhan 430065, China.

|June 28, 2023

概括

较高的全血水平与老年人轻度认知障碍 (MCI) 的风险较低有关. 增加的也与评估注意力,执行功能和语言的认知测试中的更好的表现相关.

科学领域:

神经科学是一个神经科学.
营养科学营养科学
老年学是一门学科.

背景情况:

轻度认知障碍 (MCI) 在老年人群中越来越令人担忧.
是一种必不可少的矿物质,参与许多生理过程,包括大脑功能.

研究的目的:

调查全血度与MCI的患病率之间的关联.
检查老年人度和认知表现之间的关系.

主要方法:

对1006名55岁及以上的中国成年人进行的横截面研究.
通过感应联等离子体质谱法测量全血.
使用彼得森标准诊断的MCI,包括认知衰退和神经心理测试 (TMT-B,AVLT,DSST,VFT).

主要成果:

与非MCI组相比,MCI组的含量显著降低 (p=0.017).
较高的含量与MCI的几率降低有关,与反向剂量反应关系 (OR=0.53最高与最低四分之一).
水平与口头流利性测试 (VFT) 和数字符号替换测试 (DSST) 的得分正相关,与测试 (TMT) 的得分负相关.

结论:

全血水平与中年和老年人中MCI的发生相反相关.
高度与注意力,执行功能和语言能力测试中的更好的认知功能相关.

关键词:

跨截面研究是跨截面研究.干燥的血液斑点干燥的血液斑点的含量是多少? 的含量是多少?中年和年长的成年人.轻度的认知障碍轻度的认知障碍

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