相关实验视频

Updated: Jul 25, 2025

Segmentation and Linear Measurement for Body Composition Analysis using Slice-O-Matic and Horos

Segmentation and Linear Measurement for Body Composition Analysis using Slice-O-Matic and Horos

Published on: March 21, 2021

标准的高热量,高蛋白与氨酸丰富的口服补充剂在患有癌症诱导的肉症的患者,一个随机临床试验

Aura D Herrera-Martínez^1,2, Soraya León Idougourram^1,2, Concepción Muñoz Jiménez^1,2

¹Maimonides Institute for Biomedical Research of Cordoba (IMIBIC), 14004 Cordoba, Spain.

|June 28, 2023

概括

标准的口服补充剂 (OS) 含有乳清蛋白和维生素D,可维持癌症患者的身体组成和改善功能. 氨酸丰富的OS没有显示出对癌症患者营养支持的显著额外益处.

科学领域:

在瘤学瘤学.
临床营养学临床营养学
代谢过程中的代谢.

背景情况:

癌症患者中普遍存在营养不良,对治疗结果产生负面影响.
早期营养干预对于接受全身治疗的癌症患者至关重要.
关于特定口服补充剂 (OS) 的证据,包括氨酸丰富的选择,是有限的.

研究的目的:

在癌症患者中,比较基于标准乳清蛋白的OS与氨酸丰富的OS的临床效应.
评估这些补充剂对形态功能营养状况的影响.
评估身体组成,功能和生活质量的变化.

主要方法:

开放式,受控的临床研究,包括46名接受全身治疗的癌症患者.
随机分配接受基于标准乳清蛋白的OS或12周的氨酸丰富的OS.
综合评估包括人体测量,超声波和生物化学标记;维生素D补充剂适用于所有人.

主要成果:

营养参数在两组中保持稳定;细胞外质量显示出与氨酸丰富的OS增加的趋势.
在所有患者中,功能显著改善 (p < 0.001).
标准OS组显示了前专辑蛋白,转激素和脂肪组织的增加 (p < 0.05);生活质量普遍改善 (p < 0.001).

结论:

高热量,高蛋白OS与乳清蛋白和维生素D支持维持身体组成,改善癌症患者的功能和生活质量.
在这个患者队列中,与基于标准乳清蛋白的OS相比,没有观察到氨酸丰富的OS的显著优势.

关键词:

癌症癌症癌症癌症癌症氨酸 (leucine) 是一种蛋白质.营养不良营养不良营养不良口服补充剂是一种口服补充剂.这种类型的麻症是sarcopenia.

更多相关视频

Semi-Targeted Ultra-High-Performance Chromatography Coupled to Mass Spectrometry Analysis of Phenolic Metabolites in Plasma of Elderly Adults

Semi-Targeted Ultra-High-Performance Chromatography Coupled to Mass Spectrometry Analysis of Phenolic Metabolites in Plasma of Elderly Adults

Published on: April 22, 2022

The Colon-26 Carcinoma Tumor-bearing Mouse as a Model for the Study of Cancer Cachexia

The Colon-26 Carcinoma Tumor-bearing Mouse as a Model for the Study of Cancer Cachexia

Published on: November 30, 2016

相关概念视频

mTOR Signaling and Cancer Progression

mTOR Signaling and Cancer Progression

The mammalian target of rapamycin or mTOR protein was discovered in 1994 due to its direct interaction with rapamycin. The protein gets its name from a yeast homolog called TOR. The mTOR protein complex in mammalian cells plays a major role in balancing anabolic processes such as the synthesis of proteins, lipids, and nucleotides and catabolic processes, such as autophagy in response to environmental cues, such as availability of nutrients and growth factors.
The mTOR pathway or the...

Cancer Survival Analysis

Cancer Survival Analysis

Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...