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脂蛋白脂酶活性在素食者和食肉动物的血清环境中没有差异
Natjan-Naatan Seeba1, Robert Risti1, Aivar Lõokene1
1Department of Chemistry and Biotechnology, Tallinn University of Technology, 12618 Tallinn, Estonia.
Nutrients
|June 28, 2023
概括
素食饮食不会显著改变脂肪蛋白脂酶 (LPL) 活性,以分解甘油三. 然而,素食饮食降低总胆固醇和LDL-C,表明胆固醇降低,而不是LPL变化,驱动心血管益处.
科学领域:
- 营养科学 营养科学
- 生物化学 生物化学
- 心血管健康 心血管健康
背景情况:
- 素食饮食与降低心血管疾病风险有关.
- 素食饮食对血甘油三代谢,特别是脂蛋白脂酶 (LPL) 活性的影响尚不清楚.
研究的目的:
- 为了研究素食主义者和食肉动物之间血清脂蛋白脂酶 (LPL) 活性的差异.
- 为了确定素食饮食是否通过LPL活性影响甘油三代谢.
主要方法:
- 在31个健康的素食者和食肉动物的未稀释的禁食血清样本中评估LPL活性,使用异热定位热量计.
- 分析了血清甘油三水平,总胆固醇和LDL-C.
主要成果:
- 在素食主义者和杂食群体之间没有发现平均LPL活动的显著差异.
- 素食主义者表现出较低的总胆固醇和LDL-C,与食肉动物相比.
- 在两组中都观察到LPL活性和非常低密度脂蛋白三糖体分解的显著个体变化.
结论:
- 素食饮食对心血管的益处可能源于降低胆固醇,而不是改变LPL介导的甘油三分解.
- 在健康人群中,与LPL活性相关的饮食对血清脂质组成的影响可能会被遗传或其他生活方式因素掩盖.
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