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Updated: Jun 14, 2026

Introducing a Gene Knockout Directly Into the Amastigote Stage of Trypanosoma cruzi Using the CRISPR/Cas9 System
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尼塔佐克桑化物:一种药物重新定位化合物,在小鼠模型中可能用于查加斯病

Minerva Arce-Fonseca1, Rodolfo Andrés Gutiérrez-Ocejo1, José Luis Rosales-Encina2

  • 1Laboratory of Molecular Immunology and Proteomics, Department of Molecular Biology, Instituto Nacional de Cardiología Ignacio Chávez, Juan Badiano No. 1, Col. Sección XVI, Tlalpan, Mexico City 14080, Mexico.

Pharmaceuticals (Basel, Switzerland)
|June 28, 2023
PubMed
概括

尼塔佐克桑胺在治疗夏加斯病 (ChD) 方面具有前景,通过降低寄生虫水平和预防小鼠的组织损伤. 虽然不优于本兹尼达,但其安全性概况表明它有可能作为一种替代性慢性病治疗.

关键词:
查加斯病是查加斯病的一种疾病.试osoma cruzi 是一种类型的虫.反对T.克鲁兹的代理人.药物重新定位 药物重新定位鼠标模型 鼠标模型鼠标模型尼塔佐克桑化的使用方法

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