COVID-19对非洲DTP疫苗接种趋势的影响:一个关联点回归分析
Ines Aguinaga-Ontoso1,2, Sara Guillen-Aguinaga1, Laura Guillen-Aguinaga1,3
1Department of Health Sciences, Public University of Navarra, 31008 Pamplona, Spain.
Vaccines
|June 28, 2023
概括
在非洲,COVID-19严重破坏了儿童疫苗接种,导致DTP3覆盖率下降. 这一趋势凸显了疫情对整个非洲大陆基本免疫计划的影响.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 免疫接种计划 免疫接种计划
背景情况:
- 疫苗可预防的疾病仍然是非洲儿童死亡的主要原因.
- 实现高疫苗接种率对于降低婴儿死亡率至关重要.
- 随着COVID-19大流行,医疗保健系统受到压力,可能会影响常规疫苗接种服务.
研究的目的:
- 分析2012年至2021年非洲DTP3疫苗覆盖率的趋势.
- 评估COVID-19大流行对DTP3疫苗接种率的影响.
- 确定疫苗覆盖率发生变化的特定地区和国家.
主要方法:
- 利用联合国儿童基金会数据库记录用于DTP3疫苗覆盖率数据 (2012-2021年).
- 员工结合点回归分析以确定覆盖范围的重大趋势变化.
- 计算年度百分比变化 (APC),并使用千平方测试比较2019年和2021年的覆盖范围.
主要成果:
- 在非洲,DTP3疫苗的总体覆盖率呈现出积极的趋势 (APC 1.2%) 到2019年.
- 从2019年到2021年,DTP3覆盖率的显著下降被观察到 (APC -3.5%,p < 0.001).
- 在多个撒哈拉以南非洲国家,特别是东部和南部非洲,疫苗接种率下降.
结论:
- 显然,COVID-19大流行已经破坏了非洲各地的疫苗接种.
- 2019年后,许多非洲国家的DTP3疫苗接种率显著下降.
- 这些发现强调了免疫计划对全球卫生危机的脆弱性.
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