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Sandra Felten¹, Ute Klein-Richers¹, Stefan Unterer²

¹Clinic of Small Animal Medicine, Centre for Clinical Veterinary Medicine, LMU Munich, Veterinärstrasse 13, 80539 Munich, Germany.

|June 28, 2023

概括

猫科冠状病毒 (FCoV) 在猫舍中的流放模式显示,高强度的流放者和非流放者的比以前报告的更高的比例. 某些品种和生活条件会影响猫的FCoV传播.

科学领域:

兽医病毒学兽医病毒学
猫类传染病猫类传染病
流行病学流行病学

背景情况:

猫科冠状病毒 (FCoV) 感染呈现出多种流失模式:非流失,间歇性 (低强度) 和持久性 (高强度) 流失.
猫的特有FCoV存在需要了解流放动态和相关的风险因素.

研究的目的:

为了表征FCoV在特有繁殖猫舍内猫的脱落模式.
为了确定与高强度的FCoV脱落和非脱落相关的风险因素.

主要方法:

量化逆转录聚合酶连锁反应 (RT-qPCR) 用于分析FCoVRNA的4个便样本,这些样本来自37个猫科动物的222只纯种猫.
高强度散发者被定义为猫在≥3/4样本中呈阳性;非散发者在所有四个样本中呈阴性.
风险因素分析使用了问卷数据.

主要成果:

超过一半的猫 (56.3%) 是高强度的散发者,24.3% 是非散发者,超过了之前的报道.
波斯猫对高强度脱落的风险增加;缅甸和挪威森林猫更有可能不是脱落者.
与其他猫的聚集与更高的FCoV脱落相关;较小的群体大小起到了保护因素的作用.

结论:

观察到的高强度和非分支者的更高患病率可能与住房,遗传或研究持续时间有关.
品种对高强度脱落的倾向存在,育种者卫生做法可能会影响结果.
减少猫群体规模似乎可以减轻FCoV流产频率.

关键词:

在 FCoV 病毒中,在FECVV中,FECV在FECV中在FIP中,FIP是FIP.这是RT-PCR.运营商运营商运营商运营商运营商运营商运营商运营商运营商运营商运营商运营商便便便便猫类肠道新冠肺炎病毒猫类传染性腹膜炎的发生间歇性流产间歇性流产

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