人类新陈代谢和AP-238的基本药理动力学评估:最近出现的一种阿基利皮佩拉类阿片类药物

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Updated: Jul 25, 2025

An Intestine/Liver Microphysiological System for Drug Pharmacokinetic and Toxicological Assessment
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Published on: December 3, 2020

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Pietro Brunetti1,2, Diletta Berardinelli1,2, Arianna Giorgetti2,3

  • 1Unit of Forensic Toxicology, Section of Legal Medicine, Department of Biomedical Sciences and Public Health, Marche Polytechnic University, Ancona, Italy.

Drug testing and analysis
|June 28, 2023
PubMed
概括

研究人员确定了合成阿片类药物AP-238的32种代谢物,有助于检测其使用. 这项研究提供了监测新型合成阿片类药物消费和中毒的关键生物标志物.

关键词:
高分辨率的质谱学高分辨率质谱学.人类肝脏微粒细胞新型合成阿片类药物尿路生物标志物

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