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Updated: Jul 25, 2025

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles
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了解使用生理学基础的药物动力学建模来理解他-罗克萨多斯塔特药物-药物-疾病相互作用

Jin Dong1, Luna Prieto Garcia2,3, Yingbo Huang4

  • 1Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Gaithersburg, Maryland, USA.

Clinical pharmacology and therapeutics
|June 28, 2023
PubMed
概括

基于生理学的药物动力学建模有助于预测严重慢性病 (CKD) 患者的药物药物疾病相互作用. 这项研究开发了一个虚拟的CKD人群,以评估他类药物与roxadustat的相互作用,指导安全剂量.

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