对于使用毒品的人来说,大麻素作为降低伤害的策略:快速审查
Lindsay A Lo1, Caroline A MacCallum2, Kate Nanson3
1Department of Public Health Sciences, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.
概括
大麻 (CBD) 可能有助于减少吸毒渴望和焦虑在有物质使用障碍的人. 虽然不是一种独立的治疗方法,但CBD作为一种与标准护理一起的补充性降低危害策略具有前景.
科学领域:
- 药理学 药理学是指药理学的学科.
- 成 药物 药物 药物 药物
- 公共卫生 公共卫生
背景情况:
- 北美日益升级的毒品中毒危机需要创新的减少危害策略.
- 大麻 (CBD) 正在成为有问题的物质使用个体的潜在治疗剂.
研究的目的:
- 综合目前关于CBD作为使用毒品的人的危害减轻工具的有效性的证据.
- 提供关于CBD在治疗物质使用障碍中的作用的临床和研究见解.
主要方法:
- 在主要数据库 (EMBASE,MEDLINE,CENTRAL,CINAHL) 进行了系统的文献搜索,截至2022年7月.
- 纳入标准侧重于成年人群,CBD干预物质使用或降低危害,2000年后的英语出版物和初级研究或评论文章.
- 采用叙事综合方法来分析和分组与减少危害相关的发现.
主要成果:
- 综述包括27项研究,包括5项随机试验.
- 初步证据表明,CBD可能会减少药物诱导的渴望和焦虑,特别是在阿片类药物使用障碍中.
- 低质量的研究表明,吸毒者可能会改善情绪和整体幸福感.
结论:
- 有限的证据支持CBD的实用性,作为减少渴望和与成有关的症状的辅助降害策略.
- 单独使用CBD治疗不太可能是足够的;它应该被认为是对现有治疗方案的补充.
- 进一步的研究对于在现实环境中建立最佳CBD剂量和管理至关重要.
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