较高的DeRitis比率预测了ST段升高心肌梗塞患者的心肌再输血不良
Büşra Güvendi Şengör1, Cemalettin Yılmaz2, Regayip Zehir1
1Department of Cardiology, Kartal Kosuyolu Research and Education Hospital, Istanbul, Turkey.
Angiology
|June 28, 2023
概括
较高的DeRitis比率 (AST/ALT) 与ST段升高心肌梗塞 (STEMI) 患者接受初级穿皮冠状动脉干预 (pPCI) 的心肌回血不良有关. 这种易于测量的比率可以识别高风险个体.
科学领域:
- 心脏病学 心脏病学
- 生物化学 生物化学
- 医学诊断 医学诊断 医学诊断
背景情况:
- 成功的心肌再注血对于ST段升高心肌梗塞 (STEMI) 的初级皮肤穿透冠状动脉干预 (pPCI) 后至关重要.
- 德里蒂斯比率 (AST/ALT) 是一种具有潜在预后价值的生化标志物.
研究的目的:
- 调查pPCI治疗的STEMI患者的De Ritis比率和心肌再注血之间的关联.
- 确定De Ritis比率是否可以预测pPCI后的再输血受损.
主要方法:
- 对1236名接受pPCI的STEMI患者进行了回顾性分析.
- 根据中位数 (.921) 将患者分为低和高的De Ritis比率组.
- 通过ST分段分辨率 (STR) 评估的肌心再输;<70%的STR被定义为不良的再输.
主要成果:
- 较高的De Ritis比率显著与心肌再输不良相关 (OR 10.9,P < .001).
- 支架尺寸 (OR 1.45,P = .01) 和中性粒细胞与淋巴细胞的比率 (OR 1.22,P = .03) 也与不良的再输血相关.
- 德·里蒂斯比率显示,对于心肌输液受损的强有力的预测值.
结论:
- 升高的De Ritis比率是pPCI后STEMI患者心肌再注血不良的重要预测因素.
- 由于De Ritis比率很容易获得,因此可以帮助识别STEMI患者,这些患者有较高的风险导致不充分的再输血.
- 这种标记在临床实践中为风险分层提供了一个简单的工具.
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