饮食中的和微观结肠炎的风险
Robert S Sandler1,2, Shan Sun1, Temitope O Keku1,2
1Center for Gastrointestinal Biology and Disease, Chapel Hill, North Carolina, USA.
Clinical and translational gastroenterology
|June 28, 2023
概括
更高的摄入量可能会降低微观结肠炎 (MC) 的风险. 这项研究发现MC患者的消耗较低,并将与肠道细菌的变化联系起来,这表明饮食在MC发育中的作用.
科学领域:
- 胃肠病学 胃肠病学
- 微生物组研究的研究.
- 营养科学 营养科学
背景情况:
- 微观性结肠炎 (MC) 是水性腹的日益严重的原因,特别是在老年人中.
- 饮食对MC病变发生的影响仍未得到充分研究.
研究的目的:
- 调查饮食摄入量与微观结肠炎 (MC) 之间的关联.
- 探索饮食,肠道微生物群和MC风险之间的关系.
主要方法:
- 进行了一项病例控制研究,对106例MC病例和215例对照进行了研究.
- 通过使用经过验证的食物频率问卷来评估饮食摄入量.
- 结肠活检使用16s rRNA测序分析了附着微生物.
主要成果:
- 饮食摄入量最高四分之一的个体显示,MC的风险降低.
- 饮食中的摄入量与特定肠道细菌 (Actinobacteria,Coriobacteriales) 的丰富程度显著相关.
- 与对照组相比,MC病例的饮食摄入量较低.
结论:
- 饮食中的摄入量可能在发展微观结肠炎的风险中起作用.
- 肠道微生物组合的变化可能受到饮食因素的影响,可能会影响MC风险.
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