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二氧化碳诱导的细胞外pH值下降,通过通过CREB激活在人体皮肤纤维细胞中提升TGF-β1表达的调节,增强了细胞外基因组件的产生

Kei Takano1, Shinya Kasamatsu1, Mika Aoki1

  • 1Biological Science Research, Kao Corporation, Odawara, Japan.

Experimental dermatology
|June 28, 2023
PubMed
概括

使用二氧化碳 (CO2) 的轻度皮肤酸性增强皮肤纤维细胞中的细胞外基质 (ECM) 生产. 这一过程由pH值变化,CREB激活和TGF-β1介导,表明CO2可以治疗皮肤衰老和ECM损伤.

关键词:
在TGF-β1中.二氧化碳是二氧化碳的一种物质.细胞外矩阵是细胞外矩阵.纤维细胞的细胞.它们的pH值为pH.

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