超越细胞学的哈西莫托甲状腺炎:细胞学,荷尔蒙学,血清学和放射学发现之间的相关性
Sayed Ali Almahari1, Reem Maki2, Noor Al Teraifi1
1Department of Pathology, Salmaniya Medical Complex, Rd No. 2904, Manama, Bahrain.
Journal of thyroid research
|June 28, 2023
概括
哈西莫托甲状腺炎增加了甲状腺癌的风险. 超声波和ACR TIRAD可以帮助评估结节,但修改后的系统可能会提高这些患者的准确性.
科学领域:
- 内分泌学和甲状腺学.
- 诊断成像 诊断成像 诊断成像
- 在瘤学瘤学.
背景情况:
- 哈西莫托甲状腺炎是导致慢性甲状腺炎症的主要原因.
- 诊断通常涉及超声波,细针吸收和血清标记物,如抗TPO和抗TG抗体.
- 增加的抗甲状腺过氧化酶 (TPO) 和抗甲状腺球蛋白 (TG) 抗体是常见的.
研究的目的:
- 评估哈希莫托甲状腺炎患者中瘤的发生率.
- 描述哈西莫托甲状腺炎的超声波外观,包括结节和焦点模式.
- 评估美国放射学学院 (ACR) 2017年甲状腺成像和数据系统 (TIRADS) 在哈西莫托甲状腺炎患者中的敏感性.
主要方法:
- 这是一项对137名被诊断患有哈希莫托甲状腺炎的患者进行的回顾性单一中心研究 (2013年1月至2019年12月).
- 超声波图像由放射科医生审查;细胞学报告使用贝塞斯达系统 (BSRTC 2017).
- 2017年ACR TI-RADS被用于基于超声波的风险分层.
主要成果:
- 该研究包括137名患者 (平均年龄为44.66岁,女性与男性的比例为9:1).
- 乳头甲状腺癌被诊断为8% (11例),卵泡腺瘤在0.7% (1例).
- 超声波模式包括扩散 (50%),宏 (32.2%) 和焦点结节 (17.7%);ACR TI-RADS 2017将结节从TR2到TR5.5分类.
结论:
- 哈西莫托甲状腺炎是甲状腺瘤的危险因素,需要仔细的细胞学和放射学评估.
- 识别哈西莫托甲状腺炎的可变超声波外观对于准确的解释至关重要.
- 经过修改的ACR TI-RADS系统可能有利于哈希莫托甲状腺炎患者的风险分层,以减少不必要的细针吸收 (FNA).
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