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Updated: Jul 25, 2025

Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
晚期慢性病患者的身体虚弱和功能状态:系统性审查
Priscilla Karnabi1, David Massicotte-Azarniouch1,2,3, Lindsay J Ritchie1
1Clinical Epidemiology Program, The Ottawa Hospital Research Institute, ON, Canada.
虚弱和功能状态测量与慢性病 (CKD) 患者的不良结果有关. 整合这些评估可以改善风险评估和临床决策,以获得更好的患者护理.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 老年病的医生 老年病的医生
- 公共卫生 公共卫生
背景情况:
- 全球人口老龄化和慢性病 (CKD) 患病率上升需要更新风险评估策略.
- 性在CKD患者中很常见,导致不良健康结果,但它经常被排除在临床决策之外.
研究的目的:
- 评估各种脆弱性和功能状况测量以及晚期CKD患者的死亡率和住院等结果之间的关联.
主要方法:
- 对观察研究 (队列,病例控制,横截面) 的系统审查,检查晚期CKD中的脆弱性/功能状态.
- 搜索了Medline,Embase和Cochrane中央注册到2021年3月;提取了有关人口统计,脆弱/功能状态评估和临床结果的数据.
- 包括140项研究,使用117种独特的仪器;主要关注透析患者.
主要成果:
- 虚弱和功能状况下降显著增加了不良结果的风险,包括死亡率和住院治疗.
- 所有五个个体领域的脆弱都与较差的健康结果有关.
- 大多数研究集中在透析患者群体上,只有15%的研究对非透析的CKD患者进行了检查.
结论:
- 脆弱性和功能状态的测量对于高级CKD的综合风险评估至关重要.
- 将这些措施纳入临床决策可以提高患者的护理和结果.
- 需要进一步的研究来解决方法的异质性,并提高脆弱性评估研究的严格性.
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