乳腺癌老年患者的长期结果和预后因素:单一机构的经验
Tabassum Wadasadawala1,2, Roshankumar Patil3,4, Johnny Carlton1
1Department of Radiation Oncology, Tata Memorial Centre, Homi Bhabha National Institute, Mumbai, Maharashtra 400012, India.
Ecancermedicalscience
|June 28, 2023
概括
这项研究发现,年龄的增加,瘤大小,淋巴血管入侵和分子亚型预测了老年乳腺癌患者的结果. 研究结果旨在改善管理,降低这一群体的死亡率.
科学领域:
- 在瘤学瘤学.
- 老年医学 老年医学
- 临床审计 临床审计
背景情况:
- 尽管治疗进展,老年乳腺癌患者的死亡率不断上升.
- 需要更好地了解这个人口中的预后因素.
研究的目的:
- 审计非转移性老年乳腺癌患者 (>70岁).
- 在这个患者群体中确定预测结果的预测因素.
主要方法:
- 从电子医疗记录中追溯收集数据 (n=385).
- 卡普兰-梅尔和日志等级测试的时间到事件的结果.
- 预后因素的单变量和多变量分析.
主要成果:
- 总体5年生存率为75.3%.
- 生存的独立预测因素包括年龄,瘤大小,淋巴血管侵入 (LVSI) 和分子亚型.
- 乳腺保护和全身疗法的使用不足.
结论:
- 年龄,瘤大小,LVSI和分子亚型是预测结果的关键因素.
- 在老年患者的乳房保护和全身疗法使用中发现了差距.
- 这些发现可以为老年乳腺癌患者提供改进的管理策略.
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