预测DWI-FLAIR对NCCT的不匹配:人工智能在超急性决策中的作用
Beom Joon Kim1,2, Kairan Zhu3, Wu Qiu4
1Department of Neurology, Seoul National University Bundang Hospital, Seongnam-si, Republic of Korea.
Frontiers in neurology
|June 28, 2023
概括
人工智能可以使用非对比计算断层扫描 (NCCT) 扫描来预测扩散加权成像 (DWI) 和流体减弱反转恢复 (FLAIR) 的不匹配. 这种深度学习方法有助于评估急性缺血性中风治疗的资格.
科学领域:
- 放射学 放射学是指放射学
- 人工智能的人工智能
- 神经学 神经学
背景情况:
- 扩散加权成像 (DWI) 和流体减弱倒置恢复 (FLAIR) 的不匹配对于确定急性缺血性中风中静脉血栓溶解的资格至关重要.
- 目前的临床实践受到MRI可用性和主观图像解释的限制.
研究的目的:
- 开发和评估深度学习 (DL) 模型,用于使用非对比计算断层扫描 (NCCT) 图像预测DWI-FLAIR不匹配.
- 评估DL辅助的DWI-FLAIR不匹配评估对未经验的神经病学家诊断准确性的影响.
主要方法:
- 222名急性缺血性中风患者接受了NCCT,DWI和FLAIR成像.
- 深度学习模型 (nnU-net架构) 经过训练,可以从NCCT图像中预测DWI和FLAIR病变.
- 没有经验的神经科医生评估了DWI-FLAIR在NCCT上的不匹配,有或没有DL模型的帮助.
主要成果:
- DL模型实现了Dice系数为39.1%,DWI病变的体积相关系数为0.76,FLAIR病变的体积相关系数为18.9%和0.61.
- 来自DL模型的协助提高了经验不丰富的神经病学家对DWI-FLAIR不匹配评估准确度 (AUC-ROC从0.493到0.613),特别是在较大的病变 (≥15mL) 中.
结论:
- 先进的人工智能技术可以使用NCCT图像有效估计DWI-FLAIR不匹配.
- 基于DL的预测有望提高中风治疗资格评估的可访问性和准确性.
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