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Updated: Jul 25, 2025

A Novel Feeder-free System for Mass Production of Murine Natural Killer Cells In Vitro
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p35是NK细胞细胞毒性和TGFβ介导的NK细胞功能障碍的关键参与者

Derek P Wong1, Claire E Fritz1, Daniel Feinberg1

  • 1Department of Pathology, Case Western Reserve University, Cleveland, Ohio.

Cancer research communications
|June 28, 2023
PubMed
概括

p35 (CDK5R1) 负面调节自然杀手 (NK) 细胞的细胞毒性. 抑制NK细胞中的p35增强了它们杀死癌症的能力,这表明了改善NK细胞采用疗法的新治疗标.

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