肥胖的呼吸道并发症:从早期变化到呼吸系统衰竭
Neeraj M Shah1,2,3, Georgios Kaltsakas1,2,3
1Lane Fox Respiratory Service, St Thomas' Hospital, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Breathe (Sheffield, England)
|June 28, 2023
概括
肥胖严重损害呼吸功能,减少肺体积,增加各种呼吸障碍的风险. 减肥对于改善肥胖个体的肺部健康提供了巨大的好处.
科学领域:
- 肺部病理学 肺部病理学
- 肥胖医学 肥胖医学
- 呼吸系统生理学 呼吸系统生理学
背景情况:
- 肥胖是一个日益严重的全球健康问题.
- 它是呼吸道损害的主要原因之一.
- 脂肪组织的积累影响呼吸机制和全身炎症.
研究的目的:
- 为了审查肥胖的呼吸系统后果.
- 为了阐明涉及的病理生理机制.
- 为了突出减肥对呼吸系统健康的好处.
主要方法:
- 关于肥胖和呼吸功能研究的文献综述.
- 对肥胖个体的生理变化进行分析.
- 检查与呼吸道损害相关的临床结果.
主要成果:
- 肥胖会降低静态和动态的肺体积,特别是呼气储备体积.
- 相关风险包括空气流量减少,气道过敏反应,肺高血压,栓塞,感染,阻塞性睡眠呼吸暂停和肥胖低通风综合征.
- 这些变化可以发展为低氧性或高性呼吸衰竭.
结论:
- 肥胖引起的呼吸损害源于机械负荷和全身炎症.
- 减肥明显改善了肥胖个体的呼吸道和呼吸道生理学.
- 针对体重管理的干预措施对于减轻呼吸道并发症至关重要.
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