一份关于本源冠状动脉血栓与肝素诱导的血栓塞缩症的病例报告
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Updated: Jul 30, 2026

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Ferric Chloride-induced Murine Thrombosis Models
Published on: September 5, 2016
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Cureus
|June 28, 2023
概括
低分子量肝素可以引起罕见的,严重的血栓形成 (肝素诱导的血栓缩). 这种情况应考虑在ST升高心肌梗塞患者最近暴露于氨酸.
科学领域:
- 心脏病学 心脏病学
- 血液学 血液学 血液学
- 药理学 药理学 是一个学科.
背景情况:
- 氨酸是广泛用于血栓预防和血栓栓塞治疗的抗凝剂.
- 氨酸诱导的血小板缺血 (HIT) 是治疗氨酸的一种罕见但严重的并发症.
- 如果未被识别,HIT会带来并发症和死亡的重大风险.
研究的目的:
- 报告一个罕见的多血管冠状动脉血栓形成的罕见病例,该病例是低分子量肝素诱导的血栓减小 (LMWH-HIT) 的次要病例.
- 突出LMWH-HIT作为ST段升高心肌梗塞 (STEMI) 患者最近接触LMWH的潜在差异诊断.
主要方法:
- 病例报告详细介绍了一名患有STEMI的患者.
- 调查患者最近接触低分子量肝素的情况.
- 多血管冠状动脉血栓的诊断归因于LMWH-HIT.
主要成果:
- 这位患者出现了ST段升高心肌梗塞.
- 多血管冠状动脉血栓症被确定为原因.
- 发现血栓形成是由于低分子量肝素诱导的血栓塞缩症的次要原因.
结论:
- 低分子量肝素可以通过 HIT 沉血栓,甚至在冠状动脉中.
- 在STEMI的差异诊断中应考虑HIT,特别是在最近使用LMWH的患者中.
- 早期识别和管理LMWH-HIT对于预防严重并发症至关重要.
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