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通过NSMF改变复制蛋白A结合模式对单链DNA的改变,通过ATR激酶激活RPA酸化

Yujin Kang1, Ye Gi Han1, Keon Woo Khim1

  • 1Department of Biological Sciences, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea.

Nucleic acids research
|June 28, 2023
PubMed
概括

神经元蛋白NSMF通过与DNA损伤部位的复制蛋白A (RPA) 相互作用来帮助DNA修复. NSMF促进了RPA与DNA的结合,增强了RPA32的酸化,并稳定了RPA的DNA损伤反应.

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