鼻对青少年运动引起的支气管收缩的影响
Ilia Spivak1, Guy Gut2, Moneera Hanna2
1Department of Pediatrics, Ruth Children's Hospital, Rambam Health Care Campus, Haifa, Israel.
Pediatric pulmonology
|June 28, 2023
概括
在儿童和青少年的运动挑战测试中使用鼻显著增加了运动诱导支气管收缩的检测率. 这一发现支持在这些测试中进行鼻塞的建议,以准确诊断.
科学领域:
- 儿科肺病学 儿科肺病学
- 呼吸系统医学 呼吸系统医学
- 临床试验 临床试验
背景情况:
- 在运动期间口腔呼吸可能会增加气道的高反应性.
- 关于儿童群体在运动挑战测试 (ECT) 期间需要使用鼻 (NC) 的必要性,数据有限.
- 这项研究旨在澄清NC在儿科ECT中的作用.
研究的目的:
- 评估在运动挑战测试 (ECT) 期间使用鼻 (NC) 对儿童和青少年运动诱导支气管收缩 (EIB) 检测的影响.
- 为了确定NC的使用是否会改变对EIB的ECT诊断产量.
- 评估鼻腔症状得分与阳性ECT结果之间的相关性.
主要方法:
- 采用了前性,队列研究设计.
- 儿童和青少年接受了两次单独的ECT检查:一个是使用NC,一个是不使用NC.
- 评估了肺功能 (FEV1),过敏 (TNSS) 和喘控制 (ACT).
主要成果:
- 使用NC (60.4%) 的患者在显著更高的比例上,与没有NC (33.3%) 相比,使用NC时ECT结果呈阳性.
- 使用NC导致FEV1的更大下降,并且改善了支气管扩展后的反应.
- 鼻腔症状得分并不能预测正阳性ECT的可能性.
结论:
- 在ECT期间使用鼻可提高儿科患者运动诱导支气管收缩的检测率.
- 这些发现支持儿童和青少年在ECT期间常规推鼻堵塞.
- 在这种人群中,NC的使用提高了ECT在诊断EIB的敏感性.
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