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相关概念视频

Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

474
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
474
Testes: Gross Anatomy01:19

Testes: Gross Anatomy

2.4K
The testes, also known as testicles, are the male gonads. They are housed within the scrotum, a sac-like structure located beneath the penis. The scrotum's primary role is to regulate the temperature of the testes, which is crucial for sperm production.
Each testis is surrounded by the tunica albuginea, a dense connective tissue layer that provides structural support and protection. This layer is covered by an outer serous membrane called the tunica vaginalis, which helps reduce friction...
2.4K
Testes: Histology01:27

Testes: Histology

1.1K
A tough, fibrous membrane, the tunica albuginea, covers the testes, extending inward to form fibrous partitions or septa, dividing them into internal compartments called lobules. Each lobule has 1 to 3 tightly coiled seminiferous tubules where sperm production occurs. These tubules merge into a tubular network at the back of the testis, known as the rete testis. It connects to 15 to 20 efferent ductules, leading to the epididymis.
The spermatogenic cells, responsible for producing sperm, are...
1.1K
Infertility in Males01:23

Infertility in Males

299
Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
299
Tumor Immunotherapy01:27

Tumor Immunotherapy

575
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
575

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相关实验视频

Updated: Jul 25, 2025

Teratoma Generation in the Testis Capsule
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Teratoma Generation in the Testis Capsule

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丸的瘤 丸的瘤

Susanne Krege1, Christoph Oing, Carsten Bokemeyer

  • 1Department of Urology, Pediatric Urology, and Urological Oncology, Essen-Mitte Hospital, Essen; Translational and Clinical Research Institute, Centre for Cancer, Newcastle University, Newcastle upon Tyne, UK; Department of Oncology, Hematology, and Stem Cell Transplantation, Pulmonology Section, University Hospital Hamburg Eppendorf, Hamburg.

Deutsches Arzteblatt international
|June 28, 2023
PubMed
概括

丸生殖细胞瘤在年轻男性中很常见. 多模式治疗提供了高的治愈率,在早期阶段超过99%,在晚期疾病中达到67-95%,强调量身定制的方法以避免过度治疗.

科学领域:

  • 在瘤学瘤学.
  • 泌尿器科 泌尿器科 泌尿器科 泌尿器科

背景情况:

  • 丸生殖细胞瘤是20-40岁男性中最常见的恶性瘤.
  • 德国的发病率是每年每10万名男性中有10人,总计约有4200例新病例.
  • 这些瘤在这个人口群体中代表着重大的公共卫生问题.

研究的目的:

  • 对丸生殖细胞瘤的德国临床实践指南进行审查.
  • 综合目前关于诊断,治疗和随访护理的证据.
  • 为管理这些癌症的临床医生提供基于证据的概述.

主要方法:

  • 对相关原创文章和评论进行选择性审查.
  • 根据德国关于丸生殖细胞瘤的临床实践指南的建议.
  • 专注于跨学科的管理策略.

主要成果:

  • 治疗包括丸切除,然后根据瘤类型和阶段进行监测,化疗,放射治疗或手术.
  • 三分之二的瘤在I阶段被诊断出 (仅限于丸);三分之一在诊断时是转移性 (10~15%有器官转移).
  • 基于阶段的多式疗法实现了治疗率>99%的I阶段和67-95%的晚期转移性疾病.

结论:

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  • 在早期丸生殖细胞瘤中避免过度治疗,以最大限度地减少长期副作用.
  • 对于高级阶段的强化治疗决策应该是个性化的,以优化结果.
  • 多模式治疗策略显示出高治愈率,即使在转移性疾病患者中也是如此.