在CKD患者中,饮食炎症指数与维生素D有关
Wenhui Wu1, Xiurong Li1, Jia Di1
1Department of Nephrology, The Third Affiliated Hospital of Soochow University, No. 185 Juqian Road, Changzhou, 213003, Jiangsu Province, China.
International urology and nephrology
|June 28, 2023
概括
促炎症饮食与慢性病 (CKD) 患者的维生素D水平降低有关. 对抗炎症食品的饮食改变可能有助于在CKD中保持维生素D状态.
科学领域:
- 营养科学 营养科学
- 腎臟病學 (nephrology) 是一種醫學專業.
- 生物化学 生物化学
背景情况:
- 血清中25-基维生素D (25(OH) D的低水平与慢性病 (CKD) 的较差结果有关.
- 饮食,特别是饮食炎症指数 (DII) 在调节CKD患者维生素D水平方面的作用需要进一步研究.
研究的目的:
- 为了研究饮食炎症指数 (DII) 和血清25-氧维生素D (25(OH) D水平在患有CKD的成年人之间的关联.
主要方法:
- 分析了国家健康和营养检查调查 (2009-2018) 的数据.
- 包括4283名成年CKD患者,具有完整的饮食和维生素D数据.
- 从24小时的饮食回忆中计算DII得分,并应用多变量回归和子组分析.
主要成果:
- 在DII得分和25(OH) D水平之间发现了统计学上显著的负相关性 (β = -1.83,P < 0.001).
- 这种反向关系在性别,低估小球过率 (eGFR),年龄和糖尿病分层的子组中持续存在.
- 在25(OH) D水平上,没有观察到DII和低eGFR之间的显著相互作用 (P = 0.464).
结论:
- 在CKD患者中,更高的对抗炎症饮食的坚持独立地与较低的血清25(OH) D水平有关.
- 实施抗炎饮食模式可能是减轻CKD患者维生素D减少的可行策略.
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