评估状细胞数据收集计划的歧视能力的行政索赔案例定义在识别成年人与状细胞疾病:验证研究验证研究
Ashima Singh1, Marci K Sontag2, Mei Zhou3
1Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, United States.
JMIR public health and surveillance
|June 28, 2023
概括
状细胞数据收集 (SCDC) 计划
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 医疗信息学 医疗信息学
背景情况:
- 状细胞疾病 (SCD) 是一种遗传性疾病,没有普遍的临床注册表来估计患病率.
- 疾病控制和预防中心的状细胞数据收集 (SCDC) 计划使用行政索赔来识别患有SCD的个人.
- SCDC病例定义的表现已在儿童群体中得到验证,但未在成人中得到验证.
研究的目的:
- 评估SCDC行政索赔案例定义的准确性,以确定成人SCD病例.
- 使用医疗补助保险索赔数据评估SCDC案例定义的歧视能力.
主要方法:
- 利用了来自阿拉巴马州,乔治亚州和威斯康星州的医疗保险申请和医院医疗记录 SCDC成人 (≥18岁) 计划.
- 通过将Medicaid和临床机构记录中的个人包括在内,验证了SCDC的定义.
- 采用临床实验室测试和诊断算法来确认真正的SCD状态,报告积极的预测值 (PPV).
主要成果:
- 一项为期5年的分析确定了1219人,在实验室确认的SCD病例中,总体PPV为88.4%.
- 在5年期间,阿拉巴马州和乔治亚州的数据显示,PPV分别为91%和87%.
- 包括威斯康星州在内的3年分析确定了1432名总体PPV为89.4%的个人 (阿拉巴马州:92%,佐治亚州:93%,威斯康星州:81%).
结论:
- SCDC病例定义在从行政索赔数据中识别患有SCD的成年人方面表现出很高的准确性.
- 行政索赔是识别成人SCD病例和了解其流行病学和医疗保健使用的宝贵资源.
- 有活跃SCD计划的医院提高了SCD识别的行政索赔数据的可靠性.
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