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Updated: Jul 25, 2025

Real-Time Quantification of the Effects of IS200/IS605 Family-Associated TnpB on Transposon Activity
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Real-Time Quantification of the Effects of IS200/IS605 Family-Associated TnpB on Transposon Activity

Published on: January 20, 2023

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对 ShCAST 系统的 TnsB 转子子分裂和集成的机制性见解

Ting Zeng1, Jie Yin2, Ziwen Liu1

  • 1State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China; Department of Pharmacology, School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China.

Cell reports
|June 28, 2023
PubMed
概括

类型V-K的CRISPR关联转子 (CAST) 能够实现可编程DNA集成. 这项研究阐明了转移酶TnsB和TnsC如何协同工作以实现精确的基因插入,从而扩大了CRISPR工具的应用.

关键词:
CP: 微生物学 微生物学科普:分子生物学 分子生物学与CRISPR相关的转位子在TnsBB上,我们可以看到.特定地点的基因插入.转换酶可以转换.

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