秘鲁北部海岸的SARS-CoV-2血清流行:第一波疫情后的横截面研究
Luz M Moyano1,2,3, Angie K Toledo4,5, Jenny Chirinos4
1Escuela de Medicina Humana, Universidad Cesar Vallejo, Piura, Piura, Peru.
PLoS neglected tropical diseases
|June 28, 2023
概括
这项研究发现,秘鲁Tumbes近25%的个人在第一波疫情后具有COVID-19抗体. 发烧和咳等症状与阳性抗体测试有很强的关联,突出了传播模式.
科学领域:
- 流行病学 流行病学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 秘鲁经历了高负担的COVID-19病例和死亡,在拉丁美洲排名第二.
- 图姆贝斯地区是一个边境地区,卫生和饮用水的供应有限,COVID-19死亡率高.
- 在最初的波浪之后,记录了大量的COVID-19病例和死亡.
研究的目的:
- 在秘鲁Tumbes的一个非正式定居点,在第一波疫情后确定COVID-19的血清流行率.
- 为了确定与COVID-19感染相关的社会人口因素.
- 分析与阳性COVID-19抗体测试相关的症状.
主要方法:
- 一项横截面研究于2020年11月11日至30日在Tumbes进行.
- 系统的随机抽样包括来自四分之一家庭的两岁以上的个体.
- 采集了手指刺伤血液样本进行抗体检测,并进行人口普查和症状调查. 进行PCR-RT测试,每户成年人进行1人.
主要成果:
- COVID-19的整体血清流行率为25.59%,调整后的血清流行率为24.82%.
- 与男性 (21.11%) 相比,女性的调整血清流行率 (28.03%) 较高.
- 发烧,一般不适,咳,鼻塞,呼吸困难,头痛,厌氧和老年症等症状与阳性抗体测试有显著的关联.
结论:
- 该研究强调了Tumbes地区COVID-19的传播动态.
- 调查结果为卫生部提供了有价值的数据,以加强监测和监测策略.
- 了解血清流行率和相关症状可以为未来的呼吸道疾病公共卫生干预提供信息.
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