卵细胞代谢功能,脂质组成和发育潜力因饮食而改变,在老年马匹中
Giovana D Catandi1, Lance LiPuma2, Yusra M Obeidat3
1Equine Reproduction Laboratory, Department of Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA.
概括
短期的食补充剂显著改善了老年马的卵细胞功能. 生殖支持补充剂 (RSS) 增强了代谢活动,降低了脂质含量,并增加了卵细胞的发育潜力.
科学领域:
- 生殖生物学 生殖生物学
- 动物科学动物科学
- 营养科学 营养科学
背景情况:
- 食补充剂是一种可行的方法来增强卵细胞功能和发育潜力.
- 年龄较大的母马经常经历卵细胞质量下降,影响生殖成功.
研究的目的:
- 研究短期饮食补充剂对卵细胞代谢功能,脂质组成和老年马的发育潜力的影响.
- 为了确定特定的生殖支持补充剂 (RSS) 是否可以积极改变卵细胞特征.
主要方法:
- 在大约8周的时间内,从年长的母马的成熟主导毛囊中收集卵子.
- 对照组接受了干草 (CON) 或干草和谷物 (COB).
- 在不同的实验中,接受治疗的组接受了RSS,RSS是脂肪酸和抗氧化剂的混合物,在不同的实验中,抗氧化剂水平或脂肪酸比例 (n-3至n-6) 发生了变化.
主要成果:
- 补充RSS的马卵细胞表现出更高的基础氧气消耗,表明与COB相比有氧代谢增加.
- 补充RSS导致卵细胞脂质丰度显著减少.
- 从RSS补充的马匹中注射精子的卵细胞显示出比COB马匹更高的胚胎细胞发育率.
结论:
- 短期的食补充可以直接改善老马的卵细胞功能.
- 生殖支持补充剂 (RSS) 增强卵细胞代谢活动和发育潜力,同时降低脂质含量.
- 饮食干预为改善老年马的生殖结果提供了一个有希望的策略.
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