慢性鼻炎中的鼻内三角管功能:一篇综述
Anna Kristina Hernandez1,2,3, Thomas Hummel1
1Smell and Taste Clinic, Department of Otorhinolaryngology, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Expert review of clinical immunology
|June 28, 2023
概括
慢性鼻炎 (CRS) 影响鼻内三角膜敏感性,影响生活质量. 了解这种联系对于更好的CRS症状管理和治疗策略至关重要.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 神经科学是一个神经科学.
- 免疫学 免疫学 免疫学
背景情况:
- 慢性鼻炎 (CRS) 影响5-12%的人口,严重影响生活质量.
- 在CRS中慢性炎症越来越多地被认为会影响鼻内三角管敏感性.
- 嗅觉和三神经功能之间的相互作用是协同作用的,在CRS中可能会被破坏.
研究的目的:
- 系统地审查和总结有关慢性鼻炎患者鼻内三角管功能现有知识.
- 探索三功能障碍与CRS症状,评估和治疗之间的关系.
- 识别理解的差距,并建议未来的研究方向.
主要方法:
- 在2023年2月进行了系统的文献搜索.
- 搜索的数据库包括Scopus,科学网络和PubMed.
- 审查的重点是研究在CRS的背景下研究鼻内三角管功能的研究.
主要成果:
- 三关节功能障碍可能会导致CRS中鼻腔阻塞的感知,超出物理阻塞.
- 三胞胎功能障碍的潜在机制包括免疫介导的神经损伤和神经生长因子的改变.
- 在CRS中三关节功能障碍的病理生理学尚不清楚.
结论:
- 目前对CRS的治疗主要针对潜在的炎症,对三角管功能的影响尚不清楚.
- 需要进一步的研究来阐明CRS中三功能障碍的机制.
- 对于未来的研究,建议开发标准化的临床三角体测试.
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