唐氏综合征成年人的睡眠评估:功能性和多睡眠学发现之间的相关性
Marilia Rezende Callegari1, Kelly Brito Dos Santos1, Barbara Valente de Oliveira1
1Universidade Presbiteriana Mackenzie, Centro de Ciências Biológicas e da Saúde, São Paulo SP, Brazil.
Arquivos de neuro-psiquiatria
|June 28, 2023
概括
患有唐氏综合征 (DS) 的成年人经历了显著的睡眠障碍,包括增加唤醒和睡眠呼吸障碍 (SDB). 这些睡眠问题会对他们的整体功能和行为产生负面影响.
科学领域:
- 神经科学是一个神经科学.
- 睡眠医学 睡眠医学
- 遗传学 遗传学 是一个
背景情况:
- 睡眠障碍会对健康产生不利影响,导致神经认知问题,心血管疾病和肥胖.
- 睡眠质量对整体福祉和发展至关重要,特别是在弱势群体中.
研究的目的:
- 为了研究患有唐氏综合征 (DS) 的成年人的睡眠模式.
- 在这个人群中,将观察到的睡眠变化与功能能力和行为特征相关联.
主要方法:
- 一项涉及22名患有DS的成年人 (年龄大于18岁) 的横截面研究.
- 睡眠质量通过匹兹堡睡眠质量指数进行评估,功能独立性和行为通过功能独立性测量和优点和困难问卷进行评估.
- 怀疑有睡眠障碍的11名参与者接受了多睡眠学.
主要成果:
- 100%的参与者表现出睡眠结构受损,其特点是觉醒的增加和缓慢波睡眠的减少.
- 睡眠呼吸障碍 (SDB) 的高患病率,呼吸暂停-呼吸暂停指数 (AHI) 的平均值较高.
- 睡眠质量与整体功能,认知功能和个人护理之间发现了负相关性;与睡眠不佳相关的行为变化.
结论:
- 患有唐氏综合征的成年人表现出明显的睡眠质量受损.
- 睡眠障碍,包括SDB,对DS个体的功能和行为方面产生负面影响.
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