在科巴拉明缺乏症中非自愿运动
Hamit Özyürek1, Hulya Ince2, Haydar Ali Tasdemir3
1Pediatric Neurology, Ankara City Hospital, Ankara, Turkey.
Klinische Padiatrie
|June 28, 2023
概括
患有维生素B12缺乏症的婴儿可能会发展非自愿的运动. 这些运动可能会在补充剂期间或之前出现,并且通常会在克洛纳泽帕姆治疗后消失,这凸显了诊断可巴拉明缺乏症的重要性.
科学领域:
- 儿科神经学 儿科神经学
- 营养神经科学 营养神经科学
- 发育儿科 发育儿科
背景情况:
- 营养维生素B12 (科巴胺) 缺乏是婴儿神经系统问题的已知原因之一.
- 关键的神经学后果包括发育迟缓,回归和非自愿的运动.
研究的目的:
- 调查科巴胺缺乏婴儿非自愿运动的特征.
- 为了比较与维生素B12补充剂相比,非自愿运动的发作.
主要方法:
- 对被诊断患有可巴拉明缺乏症的婴儿医疗记录的回顾性审查.
- 强迫运动的婴儿被分为两组:在补充剂期间发展运动的婴儿 (I组) 和补充剂之前的婴儿 (II组).
主要成果:
- 在32名库巴拉明缺乏的婴儿中,12名婴儿表现出非自愿的运动.
- 第一组 (n=6) 和第二组 (n=6) 显示出不同的运动模式,第二组主要表现出choreoathetoid运动,抽,肌和震.
- 这两组的非自愿运动在克洛纳泽帕姆治疗后1至3周内消失.
结论:
- 早期识别营养科巴胺缺乏症对于准确的婴儿非自愿运动差异诊断至关重要.
- 从发作或其他原因区分科巴拉明缺乏症可以防止不必要的侵略性治疗.
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