一种特定的RAGE结合可以通过阻断Erk1/2/NF-κB通路来抑制三阴性乳腺癌的生长

Xiaoyong Dai1, Yibo Hou1, Ting Deng1

  • 1Institute of Biopharmaceutical and Health Engineering, Shenzhen Key Laboratory of Gene and Antibody Therapy, State Key Laboratory of Chemical Oncogenomics, Shenzhen International Graduate School, Tsinghua University, Shenzhen, Guangdong, 518055, China.

概括

一种新型的类药物RP7在治疗侵袭性三阴性乳腺癌 (TNBC) 中表现有前途. RP7针对高级糖化终产品 (RAGE) 的受体,抑制瘤生长和扩散,没有毒性.

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