在急性和慢性肝衰竭中的预后模型
Daniela Goyes1, Hirsh D Trivedi2, Michael P Curry3
1Department of Medicine, Loyola Medicine - MacNeal Hospital, Berwyn, IL, USA.
Clinics in liver disease
|June 28, 2023
概括
急性至慢性肝衰竭 (ACLF) 呈现严重的肝功能障碍和高死亡率. 本综述探讨了定义和分类ACLF的预后模型,以帮助临床管理和研究比较.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 临床医学 临床医学
- 关键护理医学 关键护理医学
背景情况:
- 急性至慢性肝衰竭 (ACLF) 是一种严重的临床综合征.
- 以肝功能障碍和末期肝病多器官衰竭为特征.
- 与快速进展和高短期死亡率有关.
研究的目的:
- 审查ACLF的常见预后模型.
- 为定义和分类ACLF提供见解.
- 为了应对对比较研究和标准化管理的挑战.
主要方法:
- 对ACLF的预后模型的文献综述.
- 定义和分级系统的分析.
- 对ACLF预测的当前知识的综合.
主要成果:
- 缺乏统一的ACLF定义阻碍了研究.
- 对于ACLF,存在各种各样的预后模型.
- 预测ACLF结果仍然是一个挑战.
结论:
- 标准化的定义和分级对于ACLF研究至关重要.
- 预后模型是管理ACLF患者的重要工具.
- 为了改善患者的治疗结果,需要进一步就ACLF预测达成共识.
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