在急性或慢性肝衰竭中的细菌感染
Simone Incicco1, Paolo Angeli1, Salvatore Piano1
1Department of Medicine (DIMED), Unit of Internal Medicine and Hepatology (UIMH), University Hospital of Padova, Via Giustiniani 2, Padova 35128, Italy.
Clinics in liver disease
|June 28, 2023
概括
细菌感染 (BI) 的及时诊断和治疗对于急性至慢性肝衰竭 (ACLF) 患者至关重要. 经验性抗生素治疗,覆盖多抗药生物体,改善了ACLF与BI的存活率.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
背景情况:
- 细菌感染 (BIs) 是急性至慢性肝衰竭 (ACLF) 的主要触发因素和常见并发症.
- 两种药物显著恶化了ACLF的预后,增加了死亡率.
- 有效的BI管理对于改善ACLF患者的治疗结果至关重要.
研究的目的:
- 审查目前关于管理ACLF的细菌感染的证据.
- 强调在ACLF中及时诊断和治疗BI的重要性.
- 突出需要经验性抗生素治疗,涵盖多药耐药生物体的需要.
主要方法:
- 对当前证据的文献综述.
- 在ACLF中分析BI的管理策略.
- 专注于经验性的抗生素治疗.
主要成果:
- 及时诊断和治疗BI改善了ACLF的生存率.
- 经验性抗生素治疗是ACLF管理的基石.
- 抗生素耐药性需要广泛覆盖.
结论:
- 在ACLF患者中,细菌感染需要紧急注意.
- 适当的经验性抗生素治疗对于ACLF生存至关重要.
- 管理策略必须解决日益增长的抗生素耐药性.
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