[关于血喷射和血激活水对Streptococcus mutans的灭菌作用的研究]
Si Qin1, Running Wang1, Hu Li1
1School of Electrical Engineering, Guangxi University, Nanning 530004, P. R. China.
概括
血喷射 (PJ) 和血激活水 (PAW) 能够有效消毒菌突变菌 (Streptococcus mutans),这是牙的一个关键细菌. PJ提供了低电压的非热杀菌,而PAW更快,但会产生可能对牙有害的酸性环境.
科学领域:
- 生物医学工程 生物医学工程
- 等离子体物理学的物理学
- 微生物学 微生物学
背景情况:
- 牙损伤是一种普遍的口腔疾病,主要是由Streptococcus mutans引起的.
- 目前治疗牙损伤的方法有局限性,需要新的方法.
- 基于等离子体的技术为口腔病原体提供了有前途的非热杀菌方法.
研究的目的:
- 为了研究血喷射 (PJ) 和血激活水 (PAW) 在杀菌Streptococcus mutans.中的功效.
- 为了比较PJ和PAW治疗的有效性和最佳参数.
- 为了评估这些治疗对温度和pH值的影响,对潜在的牙科应用.
主要方法:
- 使用大气压等离子激发系统产生PJ和PAW.
- 在不同激发电压和时间下评估了S. mutans的灭菌率.
- 在PJ和PAW治疗期间监测温度和pH值的变化.
主要成果:
- PJ在8kV和120s时实现了S. mutans的完全灭菌,在7kV和60s时实现了统计学上显著的减少.
- PAW在9kV和60s时实现了完全灭菌,在7kV和30s时实现了统计学上显著的减少.
- 这两种方法都证明了非热杀菌 (最大温度上升<4.3°C);PAW处理将pH降至3.02.
结论:
- 最佳PJ绝育参数为8kV和90-120s;最佳PAW参数为9kV和30-60s.
- PJ需要更低的电压进行灭菌,而PAW则更快,但由于酸性而带来牙侵蚀的风险.
- 这些发现为使用等离子体技术治疗牙提供了基础.
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