在2014年美国FDA安全沟通后,丸激素处方的纵向模式
Joint Commission journal on quality and patient safety
|June 28, 2023
概括
在2014年FDA安全沟通后,标签上和标签之外的丸激素处方减少了. 非标签使用的下降与医生的特征有关,与标签处方不同.
科学领域:
- 内分泌学 在内分泌学.
- 医疗保健服务研究 医疗服务研究
- 药物监督 药物监督 药物监督
背景情况:
- 2014年美国食品和药物管理局 (FDA) 的安全沟通促使的处方模式发生了变化.
- 了解这些变化及其根据医生特征的变化对于临床实践和患者安全至关重要.
研究的目的:
- 分析2014年FDA安全沟通后丸激素处方率的变化.
- 为了调查这些处方变化是如何根据医生专业和附属关系而有所不同.
主要方法:
- 使用了20%的医疗保险服务费行政索赔数据 (2011-2019) 样本.
- 包括150万名男性受益者和58000名处方的医生.
- 采用线性细分模型来评估处方变化及其与医生/组织因素的关联,考虑冠状动脉疾病 (CAD) 和阴性腺体缺陷状态.
主要成果:
- 随着FDA的沟通,非标签的丸激素处方在患有CAD的患者下降了0.22pp,在没有CAD的患者下降了0.16pp.
- 标签上和标签之外的丸激素处方趋势都显示出最初的下降,标签外使用量每季度增加,而标签上使用量则下降.
- 医生的专业 (初级保健) 和与教学医院的联系与非标签处方的较大下降相关.
结论:
- 在标签上和标签之外的丸激素治疗,在FDA安全性传播后出现了减少.
- 医生特征影响了非标签丸激素处方的变化,但不是标签处方模式.
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