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重灌疗法后的急性缺食症:一个潜在的试点队列研究
Ellie Minchell1,2,3, Anna Rumbach4, Anna Farrell4,5
1School of Health and Rehabilitation Sciences, The University of Queensland, Brisbane, Australia. ellie.minchell@uq.net.au.
Dysphagia
|June 28, 2023
概括
在中风再注射疗法后,急性消化不良非常普遍,持续长达72小时. 吞困难与内血管血栓切除术 (EVT) 中通过的次数有关.
科学领域:
- 神经学 神经学
- 脑卒中康复治疗 脑卒中康复治疗
- 吞障碍 吞障碍 吞障碍
背景情况:
- 缺食症是中风后的一个常见并发症.
- 再 perfusion 疗法,包括内血管血栓切除术 (EVT) 和血栓溶解,正在推进中风治疗.
- 缺血症的急性模式和进展后再输血治疗仍未得到充分研究.
研究的目的:
- 为了调查急性消化不良的进展在反疗法后的72小时内.
- 探索中风参数和失足症严重程度之间的关系.
主要方法:
- 在澳大利亚两个中心对26名接受EVT和/或血栓溶解的患者进行前性研究.
- 在治疗后0-24小时,24-48小时和48-72小时使用Gugging Swallowing Screen (GUSS) 进行失消症查.
- 分析消化不良和心脏病发作大小之间的相关性,以及诸如EVT通过等程序因素.
主要成果:
- 观察到缺食症的高发病率:92.31%在24小时内,91.30%在48小时内,90.91%在72小时内.
- 在15名患者 (0-24小时),10名患者 (24-48小时) 和10名患者 (48-72小时) 中存在严重的消化障碍.
- 缺食症的严重程度与EVT (p=0.009) 中所需的通过次数有显著的相关性,但不是心脏病发作的大小.
结论:
- 缺血症在急性中风患者中仍然是一个持久的问题,尽管再注射疗法取得了进展.
- 通过EVT的次数是与失消症严重程度相关的重要因素.
- 需要进行进一步的研究,以制定针对反输后失足症的具体管理方案.
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