母亲的种族主义经历和文化认同与后代的端粒长度有关
Zaneta Thayer1, Laia Becares2, Emma Marks3
1Department of Anthropology, Dartmouth College, Hanover, NH, USA. zaneta.thayer@dartmouth.edu.
Scientific reports
|June 28, 2023
概括
毛利母亲所经历的种族主义,特别是身体攻击,与孩子的端粒长度缩短有关,这表明细胞衰老加速. 积极的文化认同可能会提供保护作用,表明干预的途径.
科学领域:
- 公共卫生 公共卫生
- 遗传学 遗传学 是一个
- 社会学 社会学 社会学
背景情况:
- 种族主义是个人及其后代健康的重要决定因素.
- 加快端粒缩短,细胞衰老的标志物,是一个潜在的生物学机制,将父母的种族主义暴露与后代的健康结果联系起来.
- 了解这些代际影响对于解决健康不平等至关重要.
研究的目的:
- 为了研究母亲的种族主义经历和后代的端粒长度之间的纵向关系.
- 探索母亲的文化联系与后代的端粒长度之间的关联.
- 检查这些协会在阿托亚罗亚新西兰的多民族队伍内.
主要方法:
- 长度评估母亲一生经历的怀孕期间的种族动机攻击.
- 测量后代的端粒长度在4.5岁时.
- 统计建模调整社会经济地位,健康状况和其他共同变量在多民族出生队列 (毛利,太平洋,亚洲).
主要成果:
- 报告有种族动机的身体攻击的毛利母亲的孩子的端粒长度明显较短 (B = -0.20,p = 0.01).
- 具有积极文化认同的毛利母亲的后代具有显著更长的端粒 (B = 0.25,p = 0.02).
- 在对关键共变量进行调整后,观察到这些关联.
结论:
- 种族主义,特别是以种族为动机的身体攻击,与后代的细胞衰老加速有关,有助于健康不平等.
- 积极的文化认同可能会起到保护作用,促进儿童的端粒长化.
- 调查结果强调需要在临床护理和政策中解决种族主义问题,并探索文化认同在减轻健康差异方面的好处.
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