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在形光受体中对基因组工程的时空空间控制

Nan-Kai Wang1,2, Pei-Kang Liu3,4,5,6, Yang Kong3

  • 1Edward S. Harkness Eye Institute, Department of Ophthalmology, Columbia University Irving Medical Center, New York, NY, 10032, USA. wang.nankai@gmail.com.

Cell & bioscience
|June 28, 2023
PubMed
概括

研究人员开发了新的可诱导的CreERT2小鼠模型,用于研究形光受体细胞. Arr3P2ACreERT2模型为视网膜研究提供100%的圆特异性和早期诱导.

关键词:
这是一种2A.在3月3日被捕他被逮捕了,被捕了.在Cre-LoxP重组组合过程中.创建2ERT2 的时间.

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Because the DNA segments are cut and reorganized in a direction-specific manner, site-specific recombination has emerged as an efficient genetic engineering technique. Flippase and Cyclization recombinases or Flp and Cre, respectively, are two members of the tyrosine recombinase family derived from bacteriophages, that are used to mediate site-specific DNA insertions, deletions, and targeted expression of proteins in mammalian cell lines.
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