机会性丝状真菌的新出现的皮下真菌:西北西班牙的一项回顾性研究
Ana Taibo1, Alejandro Seoane Estévez2, Nieves Martínez Campayo1
1Department of Dermatology, University Hospital of A Coruña, A Coruña, Spain.
Mycoses
|June 29, 2023
概括
机会主义丝状真菌会在免疫受损患者中引起新出现的皮下真菌菌. Fusarium solani感染的死亡率很高,阳性血液培养显著与死亡有关.
科学领域:
- 医学真菌学 医学真菌学
- 传染性疾病 传染性疾病
- 皮肤病学 皮肤病学
背景情况:
- 由机会性丝状真菌引起的皮下真菌病在发达国家正在增加.
- 现有的证据主要依赖于案例报告和小案件系列.
研究的目的:
- 为了估计机会性丝状真菌引起的皮下真菌病的发病率.
- 为了确定涉及的真菌物种和诱导临床变量.
- 分析与死亡率相关的因素.
主要方法:
- 观察性回顾性研究.
- 纳入标准:在2017年至2022年期间诊断出机会性丝状真菌引起的皮下真菌病.
- 临床变量和死亡率相关性的分析.
主要成果:
- 包括15名患者 (平均年龄为61岁,80%为男性).
- 阿尔特纳里亚种类,Scedosporium apiospermum和Fusarium solani是常见的分离物.
- Fusarium solani感染的死亡率为66.7%;阳性血液培养与死亡率显著相关 (p < .001).
- 最常见的表现是下肢上的性结节;免疫抑制,皮质类固醇,创伤和移植是危险因素,但与死亡率无关.
结论:
- 与hyalohyphomycosis相比,phaeohyphomycosis的传播风险较低.
- 医生需要意识到这些感染的严重程度,以防止错误诊断和治疗延迟,特别是在hyalohyphomycosis.
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