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Updated: Jul 25, 2025

CRISPR-Mediated Reorganization of Chromatin Loop Structure
09:20

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Published on: September 14, 2018

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MATR3-antisense LINE1 RNA网状结构架构高阶染色体组织

Yuwen Zhang1, Xuan Cao2, Zehua Gao1

  • 1Key Laboratory of Metabolism and Molecular Medicine, Ministry of Education, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.

EMBO reports
|June 29, 2023
PubMed
概括

核矩阵蛋白MATR3和反意义LINE1RNAs形成了一个网状结构,组织色素的空间结构. 这种相互作用影响着染色质组织,并被ALS相关的MATR3突变破坏.

关键词:
三维基因组的3D基因组这就是 MATR3R3 的意义.骨髓缩侧面硬化症 (ALS) 是一种反义的LINE1 LINE1 在线观看阶段分离的阶段分离.

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