实践中的抗真菌管理:来自前性审计和反计划的见解
Laura L Bio1, Yingjie Weng2, Hayden T Schwenk3
1Department of Pharmacy, Lucile Packard Children's Hospital Stanford, Stanford, California.
Infection control and hospital epidemiology
|June 29, 2023
概括
抗真菌前性审计和反 (PAF) 确定了改善抗真菌使用的关键领域. 尽管抗生素PAF的建议比抗生素PAF少,但抗真菌建议的接受率相似,这表明有前途的管理机会.
科学领域:
- 传染性疾病 传染性疾病
- 抗微生物药物管理委员会
- 药理学 药理学是指药理学的学科.
背景情况:
- 抗菌管理计划 (ASP) 对于优化抗生素和抗真菌使用至关重要.
- 预期审计和反 (PAF) 是ASP的一个关键策略.
- 与抗生素PAF相比,关于抗真菌PAF的特性和有效性的数据有限.
研究的目的:
- 描述抗真菌前性审计和反 (PAF).
- 为了比较抗真菌和抗生素剂之间的PAF推和接受率.
- 确定影响抗真菌和抗生素PAF推和接受率的因素.
主要方法:
- 儿童医院ASP审计的回顾性队列研究 (2020年11月 - 2022年10月).
- 数据包括10,402次抗微生物审计 (17%的抗真菌,83%的抗生素).
- 使用描述性统计和比较分析来评估推和接受率.
主要成果:
- 抗真菌审计占总抗微生物审计的17%.
- 抗生素的推率高于 (29%) 的抗真菌药 (21%;P < .001).
- 对抗真菌药物和抗生素的推接受率相似;对于抗真菌药物,中止/监测建议更为常见.
结论:
- 抗真菌PAF强调了优化特定药物使用和针对医疗服务的机会.
- 抗真菌PAF,虽然产生较少的建议比抗生素PAF,显示了可比的接受率.
- 通过PAF进行的抗真菌管理为改善抗真菌利用提供了一个有希望的途径.
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