[传统中医药药物治疗疼痛的药物规则]
概括
这项研究分析了传统中医药 (TCM) 关于缓解疼痛的专利,确定了关键的草药化合物及其治疗原理. 这些发现指导了新型TCM止痛药的开发.
科学领域:
- 药理学和传统医学的医学.
- 药物发现和开发 药物发现和开发
- 知识产权分析知识产权分析
背景情况:
- 传统中医 (TCM) 提供了丰富的疼痛管理化合物的来源.
- 分析TCM专利为已建立和新兴的止痛疗法提供了洞察力.
- 国家知识产权局 (SIPO) 专利数据库包含有关TCM药物开发的有价值数据.
研究的目的:
- 从专利数据中识别和分析有效的TCM化合物来缓解疼痛.
- 了解TCM疼痛治疗的药物规则和治疗原则.
- 为研究和开发用于治疗疼痛的新型TCM药物提供参考.
主要方法:
- 从SIPO专利数据库收集关于TCM治疗疼痛的化合物的数据.
- 统计分析包括频率,协会规则,集群和复杂网络分析.
- 使用了IBM SPSS 建模器 18.3 和 SPSS 统计 26.0 进行数据分析.
主要成果:
- 识别了顶级口服 (Glycyrrhizae Radix et Rhizoma,Angelicae Sinensis Radix) 和外部 (Myrrha,Olibanum) 处方药物. 这种药物被认为是最常见的.
- 传统中医药主要是温暖的,有苦味,味和甜味.
- 口服处方中的核心药物包括Glycyrrhizae Radix和Rhizoma;外部处方包括Olibanum和Myrrha.
结论:
- 口服处方的重点是补充气,滋养血液,促进血液循环.
- 外部处方强调激活血液,解决静止,并促进气流来缓解疼痛.
- 未来的TCM疼痛药物开发应该包含精神安静和缓解抑郁的元素.
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