高度血清性癌症可以显示状体形态模仿真状体差异化的真状体形态
Hiroshi Tomonobe1, Yoshihiro Ohishi1,2, Kazuhisa Hachisuga3
1Departments of Anatomic Pathology.
The American journal of surgical pathology
|June 29, 2023
概括
高度血清癌 (HG-SC) 很少表现出状元件,它模仿状分化,但不是真正的状分化. 这一发现对于准确诊断卵巢癌至关重要.
科学领域:
- 妇科病理学 妇科病理学
- 在瘤学瘤学.
- 癌症研究 癌症研究
背景情况:
- 卵巢的高度血清癌 (HG-SC) 和子宫内膜癌 (EC) 可能具有重叠的形态特征,使差异诊断复杂化.
- "状分化"的存在往往导致EC诊断,但HG-SC可以表现出"状成分",其性质尚不清楚.
结论:
- 在HG-SC中的"状元件"并不代表真正的状分化,而是HG-SC形态谱的一部分.
- 仔细的解释和免疫组织化学面板 (p40,p53,p16,WT1) 对于区分HG-SC与状元件和EC与状分化的区分至关重要.
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