澳大利亚对心血管药物的坚持和坚持
Juliana de Oliveira Costa1, Jialing Lin1, Sallie-Anne Pearson1
1Medicines Intelligence (MedIntel) Research Program School of Population Health-Faculty of Medicine and Health/UNSW Sydney Sydney Australia.
Journal of the American Heart Association
|June 29, 2023
概括
心血管药物持续性在开始治疗后会下降,但在使用期间坚持性仍然很高. 患有多种心血管疾病的人表现出更好的持久性和对药物的坚持.
科学领域:
- 药理学和公共卫生
- 心血管医学 心血管医学
- 医疗保健服务研究 医疗服务研究
背景情况:
- 心血管疾病负担不断增加,需要有效的药物管理.
- 许多患者因多种并发的心血管疾病而接受治疗.
- 了解药物持续性和坚持性对于优化心血管疾病治疗至关重要.
研究的目的:
- 检查澳大利亚对心血管疾病药物的坚持和坚持.
- 分析抗高血压药物,他类药物,口服抗凝剂和抗血小板药物的药物使用模式.
- 调查年龄,性别和心血管多种药物的使用对坚持和坚持的影响.
主要方法:
- 对10%的澳大利亚成年人 (≥18岁) 随机样本的国家发行申请的分析.
- 鉴定2018年开始服用抗高血压剂,他类药物,口服抗凝剂或抗血小板药物的个人.
- 使用60天的允许间隔测量持久性,并通过覆盖日数比例 (PDC) 测量坚持性,长达3年.
主要成果:
- 大约五分之一的患者在90天内停止治疗;50%在第一年内停止治疗.
- 3年后的持续性很低,从17.5% (抗血小板) 到37.3% (口服抗凝剂) 之间.
- 使用多种心血管药物的患者与单剂疗法患者相比,表现出更高的持久性和坚持性.
结论:
- 心血管药物的持续性在开始后显著下降,而在积极治疗期间的坚持性仍然很高.
- 心血管多种药物的使用普遍存在,并与改善药物持久性和坚持相关.
- 需要增强长期持久性的策略,特别是对于单个心血管疾病患者.
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