对于患有关节缩多重复性先天性儿童的生长图表
Lauren C Hyer1, Emily R Shull1, Bob Fray2
1Department of Orthopedics, Shriners Children's Greenville, Greenville, SC, USA.
Clinical pediatrics
|June 29, 2023
概括
患有多发性先天性关节炎 (AMC) 的儿童的新生长图显示,他们比通常发育的同龄人要小,特别是在幼儿时期. 这些图表有助于医疗保健提供者监测AMC儿童的成长.
科学领域:
- 儿科生长和发展 儿科生长和发展
- 遗传学和罕见疾病
背景情况:
- 与典型发育 (TD) 儿童相比,患有先天性多发性关节炎 (AMC) 的儿童表现出不同的生长模式.
- 现有的增长图表不能充分代表AMC群体,阻碍了准确的增长评估.
研究的目的:
- 开发第一个AMC特定的高度/长度和体重的生长图表.
- 为了比较AMC儿童与TD儿童的成长百分位数.
主要方法:
- 对206名被诊断患有AMC的儿童的生长数据 (身高/长度和体重) 的回顾性审查.
- 开发AMC特定的增长图表,分层分布在7个百分点.
- 对AMC增长图表与已建立的TD增长图表进行比较分析.
主要成果:
- 患有AMC的儿童的身高和体重通常比TD儿童小,特别是在生命的前36个月.
- 36个月后,AMC儿童的体重接近TD儿童的第50百分位.
- 对于AMC儿童的身高/长度始终保持在TD儿童的第五百分位附近.
结论:
- 针对AMC的生长图为医疗保健提供者提供了一个客观的工具,用于监测和评估AMC儿童的生长.
- 这些图表突出显示了AMC儿童的显著和持续的生长差异,特别是在身高方面.
- 这些发现强调了需要在AMC种群中进行专门的增长监测.
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