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Updated: Jul 25, 2025

Affinity Precipitation of Active Rho-GEFs Using a GST-tagged Mutant Rho Protein GST-RhoAG17A from Epithelial Cell Lysates
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Affinity Precipitation of Active Rho-GEFs Using a GST-tagged Mutant Rho Protein GST-RhoAG17A from Epithelial Cell Lysates

Published on: March 31, 2012

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共价片段抑制了由关氨酸交换因子激活RhoA的活性

Muhammad S Hussain1, Degang Liu1, Warren J Alilain2

  • 1Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana 46202, United States.

ACS chemical neuroscience
|June 29, 2023
PubMed
概括

研究人员确定了针对RhoA (Ras同源基因家族A成员) 的小分子抑制剂,这是阻碍神经受伤后修复的关键蛋白质. 这些抑制剂对开发用于中枢神经系统损伤的新疗法充满希望.

关键词:
在Rac1Rac1中,我们可以使用Rac1Rac1.对于rho GTPases来说,这是一个很好的方法.在RhoAAA作为一种共价抑制剂.关氨酸的交换因子小分子分子小分子

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