微生物组和贝塞特病:一个系统审查
Morgane Joubert1, Marc André2, Nicolas Barnich3
1Department of Internal Medicine, Gabriel Montpied Hospital, Clermont Auvergne University, Inserm U1071, INRAe USC2018, M2iSH, Clermont-Ferrand, France. m_joubert@chu-clermontferrand.fr.
Clinical and experimental rheumatology
|June 29, 2023
概括
贝切特病 (BD) 患者表现出肠道失调,其特点是有益细菌减少和免疫反应改变. 微生物组调节,特别是用产生乳糖酸盐的细菌,在改善BD症状和免疫失调方面显示出有前途.
科学领域:
- 微生物学 微生物学
- 免疫学 免疫学 免疫学
- 遗传学 是一个遗传学.
背景情况:
- 贝塞特病 (BD) 是一种具有复杂病因的慢性炎症性疾病.
- 微生物组在BD病原发生中的作用仍然不完全理解.
结论:
- 微生物组显著影响免疫调节和表观遗传修饰在贝塞特病.
- 向微生物群,特别是生产酸盐的细菌,代表了BD的潜在治疗策略.
- 需要进一步研究BD中微生物组和免疫之间的复杂相互作用.
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