暴露对身体成分恶化的影响:一种倾向性得分匹配的队列研究
1Division of Endocrinology and Metabolism, Department of Internal Medicine, Yeungnam University College of Medicine, Hyunchung-Ro 170, Nam-Gu, Daegu, Republic of Korea. smchung@ynu.ac.kr.
概括
高血水平会恶化身体组成,增加肥胖 (AO) 和肥胖 (SO) 的风险,特别是在老年女性中. 这种暴露会影响随着时间的推移身体成分的变化.
科学领域:
- 环境健康 环境健康
- 人体生理学 人体生理学
- 老年学是一门学科.
背景情况:
- 身体组成的变化与代谢健康和衰老有关.
- 肥胖现象类型如代谢健康的肥胖 (MHO),脂肪性肥胖 (AO) 和肉骨肥胖 (SO) 有着不同的健康影响.
- 环境因素,如重金属暴露,可能会影响人体成分.
研究的目的:
- 为了研究血中 (Cd) 含量与身体成分变化之间的联系.
- 为了确定特定的人口群体在Cd诱导的身体组成恶化更高的风险.
- 为了检查与Cd暴露有关的身体组成表型的进展.
主要方法:
- 采用了一种倾向分数匹配的队列研究设计.
- 使用多频生物电阻分析来评估身体成分.
- 参与者被分为MHO,AO和SO组,随访时间超过14年.
主要成果:
- 高血Cd水平与身体组成恶化的风险增加有关.
- 在60-69岁 (HR=2.14),女性 (HR=1.46) 和具有基线AO (HR=1.63) 的人群中,风险特别高.
- 证实Cd暴露会导致从AO到SO的恶化,特别是在老年女性中.
结论:
- 暴露于会对人体组成产生负面影响,促进肥胖和肥胖的发展.
- 老年人和妇女特别容易受到对身体组成的不良影响.
- 减少暴露可能对保持健康的身体组成至关重要,特别是在高危人群中.
相关概念视频
Coronary Artery Disease I: Introduction
28
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
28
Bone Disorders
3.7K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.7K
The Periodic Table and Organismal Elements
17.5K
Elements are the smallest units of matter that cannot be broken down further by chemical processes. There are 118 known elements, but not all of these are naturally occurring, and only a few of them are essential for life. Living matter is composed primarily of carbon, nitrogen, hydrogen, and oxygen, with smaller amounts of other elements like calcium, phosphorus, potassium, and sulfur. Other elements are also necessary for life but only in trace amounts.
Periodic Table Provides Information...
Periodic Table Provides Information...
17.5K
Cardiomyopathy II: Dilated Cardiomyopathy
11
Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
11
Chronic Kidney Disease II: Clinical Manifestations
40
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
40
The Effect of Aging on Tissues
2.2K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
2.2K


